The connection between air pollution and dementia
You probably know that inhaling air pollution increases your risk of respiratory and cardiovascular conditions like asthma, lung cancer, and heart disease. Now new research indicates a possible connection to brain diseases like dementia, as well.
Though a causal connection is yet to be established, the suspected link between dementia, which includes Alzheimer’s disease, and poor air quality hinges on the size of the pollutant air particles. In general, the smaller the particle, the more harmful it is to inhale.
How these ultrafine particles attack the brain, scientists aren't sure, but a study using lab mice at the University of Southern California found that these tiny particles can penetrate a mouse’s nasal cavities and reach the brain by traveling over neurons. This caused several inflammatory reactions—including the release of “tumor necrosis factor a,” which is found in higher quantities in the brains of humans with Alzheimer’s, as compared to those without. Similarly, a study of demented dogs in Mexico City found that they more often lived in polluted areas of the city and that their brains showed higher amounts of protein amyloid, the “plaque” associated with Alzheimer’s disease.
Other epidemiological studies examined humans with heavy exposure to microscopic airborne particles to assess the link between air quality and brain health. A review of 18 long term studies from multiple countries indicated an association between high exposure to one component of air pollution and a symptom of dementia. Similarly, an imaging study found a correlation between people who live near a major highway, with higher exposure to air pollution, and decreased brain volume. A third study of elderly women found that the total volume of white matter in the brain decreased with exposure to ultrafine particles. As these studies relate to indoor air quality, oil, gas, firewood, and cigarette smoke all produce ultrafine particulates that can be inhaled.
Again, these are not controlled studies in clinical conditions, and some people may be more susceptible to dementia than others based on genetic risk. But the evidence linking air pollution, ultrafine particles, and dementia is certainly compelling.
Disclaimers
1 Airmega air purifiers have been proven to trap dust, pollen, dander in the air based on KCL(Korea Conformity Laboratories) testing. They have been tested according to the Korea Air Cleaning Association standard (SPS-KACA 002-132:2022 Modified) to measure the 0.01㎛ size of particle removal rate. It was tested on maximum airflow speed in normal room temperature and humidity conditions. The performance may vary in the actual living environment of customers. Tested with Airmega Aim, 50, 100, 150, Tower AP-1216L, Mighty AP-1512HH, MightyS AP-1512HHS, 200M, Icon, 230, 240, 250, 250S, 300, 300S, 350, 400, 400S, 450, ProX
2Our HEPA filter complies with IEST-RP-CC007 standards at speed level 1 as tested by SGS (Société Générale de Surveillance). SGS's test report only reflects SGS's evaluation of the sample and does not reflect the evaluation of the batch of goods from which the sample was taken. Tested with Airmega 100, 150, 160, Mighty AP-1512HH, MightyS AP-1512HHS, 200M, 230, 240, 250, 250S, 250 Art, 300, 300S, 350, 400, 400S, 450, ProX
3 Tested by KCL(Korea Conformity Laboratories) according to JEM 1467: 2015 condition, the concentration of acetic acid was proven to be reduced up to 99.5% in 60 minutes. Results may vary depending on actual environment. Tested with Airmega 150, Mighty AP-1512HH, 200M
4 Tested by KCL(Korea Conformity Laboratories) according to SPS-KACA002-132:2022, showed result of over 99.5% removal rate of common household gases including Ammonia, Acetaldehyde, Acetic acid, Formaldehyde, Toluene, Benzene, Nitrogen dioxide (NO₂), and Sulfur dioxide (SO₂) within 30 minutes. Results may vary in different environments and not all odors or gas particles may be removed. Tested with Airmega MightyS AP-1512HHS, 250S, 300S, 400S, 350, 450
5 Test conducted using Coway Allergen filter media (5×5 cm) placed in a polyethylene bag. The allergen solution and sample were immersed in 2 mL of phosphate buffer (100 ng/mL) prior to the reaction and heat-sealed to specimen size. The reaction was maintained at 4°C for 24 hours. Nichinichi Pharmaceutical Co., Ltd. conducted the test using ELISA to measure allergen concentration. Results may vary in actual product usage environments. Tested with Airmega Mighty AP-1512HH, 200M
6 Removal rates of Ammonia (NH₃) and Hydrogen Sulfide (H₂S) were tested in a 1 m³ chamber under EL608:2023 conditions for 30 minutes. Gas Detector Tubes were used for measurement, and testing was conducted by KCL (Korea Conformity Laboratories). Results may vary in actual product usage environments. Tested with Airmega Mighty AP-1512HH, 200M
7 Reduction rates of Naphthalene, Sulfur Dioxide, and Nitrogen Dioxide were tested using the Airmega Mighty AP-1512HH in 1㎥ chamber, following JEM-1467:2015 standards. Tests were conducted by Intertek. Actual performance may vary depending on the living environment. Tested with Airmega Mighty AP-1512HH, 200M
9 Tested by KCL(Korea Conformity Laboratories) according to SPS-KACA002-132:2022. The test was conducted with Methyl mercaptan, Isovaleraldehyde, Isovaleric acid in a 1.0±0.1 m³ chamber with a test time of 60 minutes at (24±4)°C and (46±10)% Relative Humidity. A removal ratio of over 99.5% was achieved. Results may vary depending on the actual usage environment. Tested with Airmega 350, 450
10 Tested by the Guangzhou Institute of Microbiology, exposed the filter media to protein solutions for 24 hours under ISO 4333-2022 standard. The results showed strong reduction performance: >99.79% for pollen, >99.60% for dog allergen, >99.90% for cat allergen, and >99.80% for dust mites matter allergen. Actual results may vary depending on room size, airflow, and pollutant levels. Tested with Airmega 350, 450
11 Tested by KCL(Korea Conformity Laboratories) according to SPS-KACA002-132:2022. The test was conducted in a 1.0±0.1 m³ chamber for 60 minutes at (24±4)°C and (46±10)% Relative Humidity. A removal ratio of >99.5% was achieved for Formaldehyde and Toluene in 60 minutes. Results may vary depending on the actual usage environment. Tested with Airmega 350, 450
12 Tested by Intertek. The evaluation was conducted against designated test materials: Sulfur dioxide, Nitrogen dioxide, and Naphthalene. The test was performed in a sealed 1.0×1.0×1.0 m (1.0 m³) odor chamber at a test room temperature of (23±2)°C (measured between 23.6∼23.9°C) and a test room humidity of (45±5)% R.H. (measured between 40∼48)% Relative Humidity. It met the odor removal rate of ≥99.9% for Sulfur dioxide, Nitrogen dioxide, and Naphthalene. Results may vary depending on the actual usage environment. Tested with Airmega 350, 450
